Igama:I-Tributyrin

Ukuhlolwa: 90%, 95%

Amagama afanayo: i-glyceryl tributyrate               

Ifomula Yamamolekyuli:C₁₅H₂₆O₆

Isisindo sama-molecule:302.3633

Ukubukeka: uketshezi lwamafutha oluphuzi kuya kolungenambala, ukunambitheka okubabayo

Ifomula yama-molecule ye-triglyceride tributyrate yi-C15H26O6, isisindo sama-molecule singama-302.37;

Njengesandulela se-butyric acid, i-triglyceride uhlobo lwesengezo se-butyric acid esihle kakhulu esinezakhiwo zomzimba nezamakhemikhali ezizinzile, imiphumela emibi ephephile nengeyona enobuthi. Ayixazululi nje kuphela ukushiyeka kwe-butyric acid enukayo neguquguqukayo, kodwa futhi ixazulula inkinga yokuthi kunzima ukufaka i-butyric acid ngqo esiswini iye emathunjini, ngakho-ke inokusetshenziswa okubanzi emkhakheni wokudla kwezilwane. Njengesengezo sokudla, i-triglyceride ingasebenza ngqo endleleni yokugaya ukudla yezilwane, inikeze amandla endleleni yamathumbu ezilwane, ithuthukise impilo yamathumbu ezilwane, ilawule ukusebenza kokukhula kanye nesimo sempilo yezilwane.

Izici zomphumela:

1. 100% ngokusebenzisa isisu, akukho mfucuza.

2. Nikeza amandla ngokushesha: I-butyric acid kumkhiqizo izokhishwa kancane kancane ngaphansi kwesenzo se-intestinal lipase, okuyi-short chain fatty acid. Inikeza amandla eseli le-mucosal yamathumbu ngokushesha, ikhuthaza ukukhula okusheshayo kanye nokuthuthukiswa kwe-intestinal mucosal.

3. Vikela i-mucosa yamathumbu: Ukukhula nokuvuthwa kwe-mucosa yamathumbu kuyisici esibalulekile sokuvimbela ukukhula kwezilwane ezincane. Umkhiqizo umuncwa ezindaweni zesihlahla se-foregut, i-midgut kanye ne-hindgut, okulungisa nokuvikela ngempumelelo i-mucosa yamathumbu.

4. Ukubulala amagciwane: Ukuvimbela isifo sohudo kanye ne-ileitis, Ukwandisa ukumelana nezifo zezilwane, ukulwa nokucindezeleka.

5. Khuthaza ubisi: Thuthukisa ukudla kwabazali abakhulelwe. Khuthaza i-lactate yabazali abakhulelwe. Thuthukisa ikhwalithi yobisi lwebele.

6. Ngokuhambisana nokukhula: Khuthaza ukudla kwamathole okuncelisa. Khulisa ukumuncwa kwezakhamzimba, vikela amathole, nciphisa izinga lokufa.

7. Ukuphepha kokusetshenziswa: Thuthukisa ukusebenza kwemikhiqizo yezilwane. Kuyindlela engcono kakhulu yokukhulisa ama-Antibiotic.

8. Izindleko ziphezulu: Kuphindwe kathathu ukwandisa ukusebenza kahle kwe-butyric acid uma kuqhathaniswa ne-Sodium butyrate.

Esikhundleni sokusebenzisa ama-antibiotic

Okwamanje, kunemibiko embalwa mayelana nokufakwa esikhundleni kwama-antibiotic nge-triglyceride ekhaya nakwamanye amazwe.

Ukwengezwa kwe-bacitracin zinc kanye nemithamo ehlukene ye-Tributyrin ekudleni kwamachwane kubonise ukuthi ukwengezwa kwe-bacitracin zinc ku-1 000 kuya ku-1 500 mg/kg kungathatha indawo yokwengezwa kwama-antibiotic, futhi kugcine ukusebenza kokukhula, isimo samathumbu kanye nokusebenza komzimba kwamachwane. Lapho umthamo wawungu-2 000 ~ 2 500 mg/kg, wawungeke nje kuphela uthathe indawo yama-antibiotic, kodwa futhi wawuthuthukisa kakhulu isimo samathumbu, ukusebenza kokukhula kanye nokuzivikela kwamachwane, futhi uthuthukise izinga lempilo lamachwane.

Kumathole ancelisiwe ukudla okuphindwe kabili kunezela i-butyric acid glyceride kanye namafutha e-oregano noma i-salicylic acid methyl ester kungakhuthaza inani le-V/C yamathumbu, kuthuthukise isimo samathumbu samathole, kwandise kakhulu ubuningi bomnyango wesikhunta owugqinsi, kunciphise ukuguquka kweminyango, amagciwane e-defense coli, i-escherichia, ubuningi, kushintshe isakhiwo sezitshalo zamathumbu, futhi ama-metabolites ancelisiwe impilo yamathumbu amathole ancelisiwe, angasetshenziswa kumathole ancelisiwe esikhundleni sama-antibiotic.

Ukudla okune-TB kanye nama-antibiotics kunomphumela ofanayo wokukhula kwamachwane akhumuliwe, kanti ama-triglyceride kanye nama-antibiotics anomphumela wokubambisana.