1. Izakhiwo ze-Physicochemical
I-Benzoic acid(i-benzenecarboxylic acid) iyi-asidi e-aromatic elula kakhulu ene-asidi ebuthakathaka (i-dissociation constant 4.20). Incibilika kancane emanzini kodwa incibilika kalula ezinyibilikisini eziphilayo ezifana ne-ethanol. Ngenxa ye-lipophilicity yayo enamandla, ingangena ezingxeni zamaseli ezincane futhi ibe nemiphumela yokulwa namagciwane ngokuvimbela ukumuncwa kwe-amino acid, ukuphazamisa umsebenzi we-enzyme yokuphefumula, kanye nokuvimbela ukusabela kokuminyana kwe-acetyl-CoA.

2. I-Spectrum ye-Antimicrobial: Isebenza kahle ngokumelene namagciwane, isikhunta, kanye nemvubelo, kanye nemiphumela yokulondolozwa ethuthukisiwe ikakhulukazi ezindaweni ezine-asidi (isb., uma iguqulwa ibe usawoti we-benzoate).

3. Ukwakheka kwe-Metabolism kanye nokuphepha

Ezilwaneni, i-benzoic acid isetshenziswa kakhulu esibindini, kanti ngaphezu kuka-85% ikhishwa emchameni njenge-hippuric acid, okungashiyi nhlobo insalela futhi kungaphazamisi ibhalansi ye-acid-base.
Abantu nezingulube babonisa izindlela ezifanayo zokusebenzisa umzimba, ngokukhipha cishe ngokuphelele zingakapheli amahora angama-24, okubonisa ukuphepha okuphezulu.

II. Izicelo Ezithile Kokuphakelayo

Imithethonqubo kanye namazinga omthamo

EUKusukela ngo-2003, i-benzoic acid ivunyelwe njenge-acidifier ekudleni kwezingulube ku-0.5% ~ 1.0%.
IShayina: Kubhalwe njengomlawuli we-pH kanye nowokugcina ku-Ikhathalogi Yokwengeza Okuphakelayo (2013), ngaphandle kwemingcele ecacile yesilinganiso kodwa ebhekisela ezindinganisweni zokudla ezingu-0.2 ~ 1.0 g/kg.

Imisebenzi kanye Nokusebenza Kahle

Okunye Okulwa Namagciwane: Ngemva kokuvinjelwa kwe-EU ngama-antibiotic ngo-2006, i-benzoic acid yaba yindawo ebalulekile esikhundleni sayo ngenxa yezakhiwo zayo zokulwa namagciwane ezibanzi, ikakhulukazi ekuvimbeleni isifo sohudo ngemuva kokulunyulwa (i-PWD) kanye nokuthuthukisa ukukhula kwezingulube ezincane.
Ukusebenza Kokukhula: Izifundo zibonisa ukuthi ukwengeza i-benzoic acid engu-0.5% kuthuthukisa ukudla kanye nokwanda kwesisindo ezingulubeni ezincelisayo.

Ukuqhathaniswa nezinye izithako

Uma kuqhathaniswa ne-potassium diformate, i-benzoic acid imuncwa ngokushesha kakhulu ku-foregut futhi idinga ubuchwepheshe bokumboza ukuze isebenze ku-hindgut, kuyilapho i-potassium diformate ihlasela ngqo i-duodenum, inikeza ukusebenza kahle okuphezulu kokulwa namagciwane.