Ukusetshenziswa kwama-Antibiotics njengabagqugquzeli bokukhula ekukhiqizweni kwemfuyo kuya ngokuya kugxekwa futhi kugxekwa umphakathi. Ukuthuthukiswa kokumelana kwamagciwane kuma-antibiotic kanye nokumelana kwamagciwane kubantu nasezilwaneni okuhambisana nokusetshenziswa okungafanele kwama-antibiotics okwelaphayo kanye/noma okungafanele yizinto ezikhathazayo kakhulu.

Emazweni e-EU, ukusetshenziswa kwama-antibiotic ukuthuthukisa ukukhiqizwa kwezilwane kuvinjelwe. E-US, iNdlu Yabameleli beNhlangano yaseMelika yamukele isinqumo emhlanganweni wayo waminyaka yonke ngoJuni esinxusa ukuthi ukusetshenziswa kwama-antibiotic "okungewona okwelaphekayo" ezilwaneni kuqedwe noma kuqedwe. Lesi sinyathelo sibhekisela ngqo kuma-antibiotic anikezwa abantu. Sifuna uhulumeni aqede ukusetshenziswa ngokweqile kwama-antibiotic ezilwaneni, sandise umkhankaso wenhlangano wokunciphisa ukumelana kwabantu nemithi esindisa impilo. Ukusetshenziswa kwama-antibiotic ekukhiqizweni kwezilwane kubuyekezwa nguhulumeni futhi izinyathelo zokulawula ukumelana nemithi ziyathuthukiswa. ECanada, ukusetshenziswa kweCarbadox okwamanje kubuyekezwa yiHealth Canada futhi kubhekene nokuvinjelwa okungenzeka. Ngakho-ke, kusobala ukuthi ukusetshenziswa kwama-antibiotic ekukhiqizweni kwezilwane kuzoba nemingcele kakhulu futhi ezinye izindlela zokukhulisa ama-antibiotic zidinga ukuphenywa futhi zisetshenziswe.

Ngenxa yalokho, ucwaningo luqhutshwa njalo ukuze kufundwe ezinye izindlela zokufaka esikhundleni sama-antibiotic. Ezinye izindlela ezisetshenziswayo zisukela kumakhambi, ama-probiotic, ama-prebiotic kanye nama-organic acid kuya kumakhemikhali kanye namathuluzi okuphatha. Izifundo eziningi zibonise ukuthi i-formic acid iyasebenza ngokumelene namagciwane abangela izifo. Nokho, empeleni, ngenxa yezinkinga zokuphatha, iphunga elinamandla kanye nokugqwala kokucubungula ukudla kanye nokondla kanye nemishini yokuphuza, ukusetshenziswa kwayo kunqunyelwe. Ukuze kunqotshwe izinkinga, i-potassium diformate (K-diformate) ithole ukunakwa njengendlela ehlukile ye-formic acid ngoba kulula ukuyiphatha kune-acid emsulwa, kuyilapho iboniswe isebenza kahle ekuthuthukiseni ukusebenza kokukhula kokubili kwezingulube ezilunyuliwe kanye nezikhula ngesivinini. Ucwaningo olwenziwe ngabacwaningi e-Agricultural University of Norway (J. Anim. Sci. 2000. 78:1875-1884) lubonise ukuthi ukungezelelwa kokudla kwe-potassium diformate emazingeni angu-0.6-1.2% kuthuthukise ukusebenza kokukhula, ikhwalithi yezidumbu kanye nokuphepha kwenyama ezingulubeni ezikhula ngesivinini ngaphandle kwemiphumela emibi ekhwalithini yengulube ezwelayo. Kuboniswe nokuthi ngokungafanii-potassium diformate Ukwengezwa kwe-Ca/Na-formate akuzange kube nomthelela nhlobo ekukhuleni kanye nekhwalithi yesidumbu.

Kulolu cwaningo, kwenziwe izivivinyo ezintathu. Kokuzama kokuqala, izingulube ezingu-72 (isisindo somzimba sokuqala esingu-23.1 kg kanye nesisindo somzimba esingu-104.5 kg) zanikezwa ukwelashwa okuthathu kokudla (Ukulawula, i-0.85% Ca/Na-formate kanye ne-0.85% potassium-diformate). Imiphumela ibonise ukuthi ukudla kwe-K-diformate kwandise inzuzo ejwayelekile yansuku zonke (i-ADG) kodwa akubanga nomthelela ekudleni kokudla kwansuku zonke okujwayelekile (i-ADFI) noma isilinganiso senzuzo/ukudla (i-G/F). Okuqukethwe kwe-carcass okunamafutha noma okunamafutha akuzange kuthinteke yi-potassium-diformate noma i-Ca/Na-formate.

Ekuhlolweni kwesibili, kwasetshenziswa izingulube eziyi-10 (i-BW yokuqala: 24.3 kg, i-BW yokugcina: 85.1 kg) ukutadisha umphumela we-K-diformate ekusebenzeni kanye nekhwalithi yezinzwa zengulube. Zonke izingulube zazinohlelo lokudla olulinganiselwe futhi zondliwa ukudla okufanayo ngaphandle kokwengeza i-K-diformate engu-0.8% eqenjini lokwelashwa. Imiphumela ibonise ukuthi ukwengeza i-K-diformate ekudleni kukhulisa i-ADG kanye ne-G/F, kodwa akubanga nomthelela kwikhwalithi yezinzwa zengulube.

Ekuhlolweni okuthathu, izingulube ezingu-96 (i-BW yokuqala: 27.1 kg, i-BW yokugcina: 105kg) zanikezwa ukwelashwa okuthathu kokudla, okuqukethe i-0, 0.6% kanye ne-1.2% K-diformate ngokulandelana, ukuze kufundwe umphumela wokwengeza.I-K-diformateEkudleni ngokusebenza kahle kokukhula, izici zesidumbu kanye ne-microflora yendlela yokugaya ukudla. Imiphumela ibonise ukuthi ukwengezwa kwe-K-diformate ezingeni lika-0.6% kanye nele-1.2% kwandisa ukusebenza kokukhula, kunciphisa okuqukethwe kwamafutha kanye nephesenti elithuthukisiwe lokuncipha kwesidumbu. Kutholakale ukuthi ukufaka i-K-diformate kunciphisa inani lama-coliforms endleleni yokugaya ukudla kwezingulube, ngakho-ke, kuthuthukisa ukuphepha kwengulube.